Perfil microbiológico en Diabetes y Periodontitis: Revisión sistemática.

  • Edison Andrés Cruz-Olivo Universidad del Valle / Institución Universitaria Colegios de Colombia - UNICOC https://orcid.org/0000-0001-7416-3775
  • Vanessa Jiménez´-Galeano Institución Universitaria Colegios de Colombia - UNICOC
Palabras clave: Diabetes mellitus, Diabetes tipo I, Diabetes tipo II, Hiperglicemia, Periodontitis, Porphyromonas gingivalis

Resumen

Antecedentes: Los periodontopatógenos se han asociados con ineficiente control glicémico y destrucción periodontal en pacientes diabéticos. Objetivo: Determinar el perfil microbiológico oral en pacientes con diabetes mellitus tipo 1 y tipo 2 con enfermedad periodontal. Materiales y Métodos: Estudios observacionales que evaluaron la microbióta periodontal en pacientes con diabetes y periodontitis fueron seleccionados de bases de datos electrónicas PubMed, ISI Web of Sciences, LILACs y Google Scholar para la presente revisión. Los términos de búsqueda controlados y no controlados fueron: “periodontitis, chronic periodontitis, diabetes, diabetes mellitus, type 1 diabetes, type 2 diabetes, blood glucose, glicated hemoglobin, risk factors, gingival crevicular fluid, periodontal tissue, cytokine levels, interleukin-6, tumor necrosis factor-α, reactive oxygens species, advanced glycation end products, A. actinomycetemcomitans, P. gingivalis, F. nucleatum”. Resultados: Dieciséis artículos fueron incluidos en la revisión sistemática. Los microorganismos frecuentemente encontradas en pacientes con diabetes tipo 1 y/o tipo 2 con periodontitis fueron Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, Fusobacterium nucleatum, Prevotella intermedia, Tannerella forsythia, Campylobacter rectus, Candida spp. Conclusión: Las bacterias del complejo rojo se encontraron en pacientes con diabetes tipo 1 y tipo 2 con periodontitis; específicamente la P. gingivalis y el A. actinomycetemcomitans. Identificar la microbiota oral permite orientar un tratamiento periodontal y antimicroiano específico haciéndolo más predecible.

Abstract:

Background: Periodontal pathogens has been associated with poor glycemic control and periodontal tissue destruction in diabetic patients. Objective: To determine the oral microbial profile in type 1 and type 2-diabetes mellitus patients with periodontal disease. Materials and Methods: Observational studies that evaluated the oral microbial profile in type-1 and type-2 diabetes mellitus patients were selected from electronic data bases PubMed, ISI Web of Sciences, LILACs and Google Scholar. The controlled and uncontrolled search terms for the systematic search were: “periodontitis, chronic periodontitis, diabetes, diabetes mellitus, type 1 diabetes, type 2 diabetes, blood glucose, glicated hemoglobin, risk factors, gingival crevicular fluid, periodontal tissue, cytokine levels, interleukin-6, tumor necrosis factor-α, reactive oxygens species, advanced glycation end products, A. actinomycetemcomitans, P. gingivalis, F. nucleatum”. Results: Six-teen articles were included in this systematic review. The microorganisms frequently identified both in type-1 and type-2 diabates patients with periodontal disease were Porphyromonas gingivalis, Treponema denticola, Aggregatibacter actinomycetemcomitans, Fusobacterium nucleatum, Prevotella intermedia, Tannerella forsythia, Campylobacter rectus, Candida spp. Conclusion: Red complex bacteria were found in patients with type-1 and type-2 diabetes with periodontal disease; specifically, P. gingivalis and A. actinomycetemcomitans. Due the advanced periodontal tissue destruction in diabetic patients, the understanding the oral microbiota could lead to a specific periodontal treatment with antibiotic therapy making it more predictable.

Key words: Diabetes mellitus, type 1 diabetes, type 2 diabetes, hyperglycemia, periodontitis, Porphyromonas gingivalis.

Biografía del autor/a

Edison Andrés Cruz-Olivo, Universidad del Valle / Institución Universitaria Colegios de Colombia - UNICOC

Odontólogo, Especialista en Periodoncia, Magíster en Ciencias Odontológicas, Profesor Universidad del Valle, Profesor Institución Universitaria Colegios de Colombia - UNICOC.

Vanessa Jiménez´-Galeano, Institución Universitaria Colegios de Colombia - UNICOC

Odontóloga, Especialista en Periodoncia.

Citas

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Publicado
2021-06-23
Cómo citar
Cruz-Olivo, E., & Jiménez´-GaleanoV. (2021). Perfil microbiológico en Diabetes y Periodontitis: Revisión sistemática. Salutem Scientia Spiritus, 7(2), 31-40. Recuperado a partir de https://revistas.javerianacali.edu.co/index.php/salutemscientiaspiritus/article/view/2045
Sección
Revisión sistemática de la literatura