Scales for measuring adherence to pharmacological treatment in patients with type 2 diabetes mellitus: A narrative review
Abstract
Diabetes mellitus is a metabolic disorder characterized by hyperglycemia, which if left unmanaged, is associated with damage and dysfunction of various tissues and organs. It is estimated that 422 million adults suffer from diabetes worldwide, highlighting the importance of therapeutic adherence, which refers to the extent to which a person's behavior regarding medication intake, adherence to diet, and lifestyle changes aligns with the recommendations agreed upon by a healthcare professional. This study aims to conduct a narrative review to evaluate the methods used for pharmacological adherence in patients with type 2 diabetes mellitus and thereby determine the most effective strategies for improving therapeutic adherence in patients diagnosed with type 2 diabetes mellitus.
Downloads
References
ElSayed NA, Aleppo G, Aroda VR, Bannuru RR, Brown FM, Bruemmer D, et al. 2. Classification and diagnosis of diabetes: Standards of care in diabetes-2023. Diabetes Care. 2023;46(Suppl 1):S19-40.
Harreiter J, Roden M. Diabetes mellitus - Definition, Klassifikation, Diagnose, Screening und Prävention (Update 2019). Wien Klin Wochenschr [Internet]. 2019;131(Suppl 1):6-15. DOI: 10.1007/s00508-019-1450-4
Sapkota S, Brien J-A, Greenfield J, Aslani P. A systematic review of interventions addressing adherence to anti-diabetic medications in patients with type 2 diabetes—impact on adherence. PLoS One. 2015; 10(2):e0118296. DOI: 10.1371/journal.pone.0118296
Keays R. Diabetes. Curr Anaesth Crit Care. 2007; 18(2):69-75. Disponible en: https://www.paho.org/es/temas/diabetes
American Diabetes Association Professional Practice Committee. 9. Pharmacologic approaches to glycemic treatment: Standards of Medical Care in diabetes-2022. Diabetes Care. 2022; 45(Suppl 1):S125-43.
American Diabetes Association Professional Practice Committee. 8. Obesity and weight management for the prevention and treatment of type 2 diabetes: Standards of Medical Care in diabetes-2022. Diabetes Care. 2022; 45(Suppl 1):S113-24.
Revistaalad.com. [citado el 3 de junio de 2023]. Disponible en: https://www.revistaalad.com/guias/5600AX191_guias_alad_2019.pdf
Ortega Cerda JJ, Herrera DS, Adrián Ó, Miranda R, Manuel J, Legaspi O. Adherencia terapéutica: un problema de atención médica [Internet]. Org.mx. [citado el 3 de junio de 2023]. Disponible en: https://www.scielo.org.mx/pdf/amga/v16n3/1870-7203-amga-16-03-226.pdf
María Martínez-Sánchez L, Inés Martínez-Domínguez G, Lopera-Valle JS, Vargas-Grisales N. La importancia de la adherencia terapéutica [Internet]. Scielo.org. [citado el 3 de junio de 2023]. Disponible en: http://ve.scielo.org/pdf/rvdem/v14n2/art03.pdf
Foro LA, Adherencia AL, Tratamiento, Cumplimiento Y, Constancia P, Mejorar LA, et al. La adherencia al tratamiento: cumplimiento y constancia para mejorar la calidad de vida [Internet]. Csic.es. [citado el 3 de junio de 2023]. Disponible en: http://envejecimiento.csic.es/documentos/documentos/pfizer-adherencia-01.pdf
Banday MZ, Sameer AS, Nissar S. Pathophysiology of diabetes: An overview. Avicenna J Med. 2020;10(4):174-88. DOI: 10.4103/ajm.ajm_53_20
Zheng Y, Ley SH, Hu FB. Global aetiology and epidemiology of type 2 diabetes mellitus and its complications. Nat Rev Endocrinol. 2018; 14(2):88-98. DOI: 10.1038/nrendo.2017.151
Carratalá-Munuera C, Cortés-Castell E, Márquez-Contreras E, Castellano JM, Perez-Paramo M, López-Pineda A, et al. Barriers and solutions to improve therapeutic adherence from the perspective of primary care and hospital-based physicians. Patient Prefer Adherence. 2022; 16:697-707. DOI: 10.2147/PPA.S319084
Parra DI, Romero Guevara SL, Rojas LZ. Influential factors in adherence to the Therapeutic Regime in hypertension and diabetes. Invest Educ Enferm. 2019; 37(3). DOI: 10.17533/udea.iee.v37n3e02
Marinho FS, Moram CBM, Rodrigues PC, Leite NC, Salles GF, Cardoso CRL. Treatment adherence and its associated factors in patients with type 2 diabetes: Results from the Rio de Janeiro type 2 diabetes cohort study. J Diabetes Res. 2018; 2018:1-8. DOI: 10.1155/2018/8970196
Teng CL, Chan CW, Wong PS. Medication adherence of persons with type 2 diabetes in Malaysia: A scoping review and meta-analysis. J ASEAN Fed Endocr Soc. 2022; 37(1):75-82. DOI: 10.15605/jafes.037.01.14
Orozco-Beltrán D, Mata-Cases M, Artola S, Conthe P, Mediavilla J, Miranda C. Abordaje de la adherencia en diabetes mellitus tipo 2: situación actual y propuesta de posibles soluciones. Aten Primaria. 2016; 48(6):406-20. DOI: 10.1016/j.aprim.2015.09.001
Denicolò S, Perco P, Thöni S, Mayer G. Non-adherence to antidiabetic and cardiovascular drugs in type 2 diabetes mellitus and its association with renal and cardiovascular outcomes: A narrative review. J Diabetes Complications. 2021;35(7):107931. DOI: 10.1016/j.jdiacomp.2021.107931
Morisky DE, Green LW, Levine DM. Concurrent and predictive validity of a self-reported measure of medication adherence. Med Care. 1986; 24(1):67-74. DOI: 10.1097/00005650-198601000-00007. PMID: 3945130.
Muntner P, Joyce C, Holt E, He J, Morisky D, Webber LS, Krousel-Wood M. Defining the minimal detectable change in scores on the eight-item Morisky Medication Adherence Scale. Ann Pharmacother. 2011; 45(5):569-75. DOI: 10.1345/aph.1P677. Epub 2011 Apr 26. PMID: 21521862.
Uchmanowicz B, Jankowska EA, Uchmanowicz I, Morisky DE. Self-reported medication adherence measured with Morisky medication adherence scales and its determinants in hypertensive patients aged ≥60 years: A systematic review and meta-analysis. Front Pharmacol. 2019; 10:168. DOI: 10.3389/fphar.2019.00168
Burgos-Alonso N, Torrecilla M, Mendiguren A, Pérez-Gómez Moreta M, Bruzos-Cidón C. Strategies to Improve Therapeutic Adherence in Polymedicated Patients over 65 Years: A Systematic Review and Meta-Analysis. Pharmacy (Basel). 2024; 12(1):35. DOI: 10.3390/pharmacy12010035
Mansurova JA, Orekhov A, Zhunuspekova AS, Kassymova AA, Karazhanova LK. The Impact of Patient Adherence to Dual Antiplatelet Medication Following Percutaneous Coronary Intervention on the Occurrence of Adverse Cardiovascular Events. Patient Prefer Adherence. 2024 Feb 17;18:425-434. DOI: 10.2147/PPA.S450317
Santiago-Garcia AP, Gamez-Nava JI, Avalos-Salgado FA, Cerpa-Cruz S, Amaya-Cabrera EL, Gutierrez-Ureña S, Nava-Valdivia CA, Gonzalez-Vazquez S, Arevalo-Simental DE, Gomez-Camarena JJ, Ponce-Guarneros JM, Rodriguez-Jimenez NA, Saldaña-Cruz AM, Cardona-Muñoz EG, Gonzalez-Lopez L; Research Group for Factors Related to Therapeutic Outcomes in Autoimmune Diseases. Complementary Therapies and Their Association with Problems in Therapeutic Adherence to Conventional Synthetic DMARDs in Rheumatoid Arthritis: A Cross-Sectional Study. Healthcare (Basel). 2023; 12(1):49. DOI: 10.3390/healthcare12010049
Wang Y, Lee J, Toh MPHS, Tang WE, Ko Y. Validity and reliability of a self-reported measure of medication adherence in patients with Type 2 diabetes mellitus in Singapore: Validation of a medication adherence measure in Singapore. Diabet Med. 2012;29(9):e338-44. DOI: 10.1111/j.1464-5491.2012.03733.x
Wang J, Bian R-W, Mo Y-Z. Validation of the Chinese version of the eight-item Morisky medication adherence scale in patients with type 2 diabetes mellitus. J Clin Gerontol Geriatr. 2013; 4(4):119-22. DOI: 10.1016/j.jcgg.2013.06.002
Martinez-Perez P, Orozco-Beltrán D, Pomares-Gomez F, Hernández-Rizo JL, Borras-Gallen A, Gil-Guillen VF, et al. Validation and psychometric properties of the 8-item Morisky Medication Adherence Scale (MMAS-8) in type 2 diabetes patients in Spain. Aten Primaria. 2021; 53(2):101942. DOI: 10.1016/j.aprim.2020.09.007
Beyhaghi H, Reeve BB, Rodgers JE, Stearns SC. Psychometric properties of the four-item Morisky green Levine medication adherence scale among atherosclerosis risk in communities (ARIC) study participants. Value Health [Internet]. 2016; 19(8):996-1001. DOI: 10.1016/j.jval.2016.07.001
S A, T M. Self care and medication adherence among type 2 diabetics in Puducherry, southern India: A hospital based study. J Clin Diagn Res. 2014; 8(4):UC01-3. DOI: 10.7860/JCDR/2014/7732.4256
Elhenawy YI, Abdelmageed RI, Zaafar DK, Abdelaziz AW. Adherence to insulin therapy among children with type 1 diabetes: Reliability and validity of the Arabic version of the 4-item Morisky medication adherence scale. Patient Prefer Adherence. 2022; 16:1415-21. DOI: 10.2147/ppa.s341061
Capellari C, Figueiredo AEPL. Conhecimento e Atitude: perfil de pessoas com diabetes em diálise. Rev Enferm UERJ. 2020; 28:e45261. DOI: 10.12957/reuerj.2020.45261
Torres HC, Virginia A H, Schall VT. Validação dos questionários de conhecimento (DKN-A) e atitude (ATT-19) de Diabetes Mellitus. Rev Saude Publica. 2005; 39(6):906-11. DOI: 10.1590/s0034-89102005000600006
CapellariI, C., & Figueiredo, A. E. P. L. Knowledge and attitude: profile of diabetics in dialysis.
Anderson RM, Donnelly MB, Gressard CP, Dedrick RF. Development of diabetes attitude scale for health-care professionals. Diabetes Care. 1989; 12(2):120-7. DOI: 10.2337/diacare.12.2.120. PMID: 2702894.
Lou Q, Chen Y, Guo X, Yuan L, Chen T, Wang C, et al. Diabetes Attitude Scale: validation in type-2 diabetes patients in multiple centers in China. PLoS Ono. 2014; 9(5):e96473. DOI: 10.1371/journal.pone.0096473
Vieira G de LC, Pagano AS, Reis IA, Rodrigues JSN, Torres H de C. Translation, cultural adaptation and validation of the Diabetes Attitudes Scale - third version into Brazilian Portuguese. Rev Lat Am Enfermagem. 2018; 25(0). Disponible en: https://www.scielo.br/j/rlae/a/JvN46pZWtpkMDG5LcQKRjJR/?lang=es&format=pdf
Mikhael EM, Hussain SA, Shawky N, Hassali MA. Validity and reliability of anti-diabetic medication adherence scale among patients with diabetes in Baghdad, Iraq: a pilot study. BMJ Open Diabetes Res Care. 2019; 7(1):e000658. DOI: 10.1136/bmjdrc-2019-000658
View of drug non-adherence in type 2 diabetes mellitus; predictors and associations [Internet]. Edu.pk. [citado el 6 de junio de 2023]. Disponible en: https://jamc.ayubmed.edu.pk/jamc/index.php/jamc/article/view/394/285
Gonzalez JS, Tanenbaum ML, Commissariat PV. Psychosocial factors in medication adherence and diabetes self-management: Implications for research and practice. Am Psychol. 2016; 71(7):539-51. DOI: 10.1037/a0040388
Trani MR, Bilocura I, Bersabal S, Panilagao RK, Toledo BR, Garrido E, Aultman C, Oh P, Ghisi GLM. Effects of a comprehensive structured patient education intervention on disease-related knowledge and behaviour change among people living with type 2 diabetes in the Philippines. Front Rehabil Sci. 2024; 5:1374850. DOI: 10.3389/fresc.2024.1374850
The biggest source of information for doctors - proLékaře.cz [Internet]. Prolekare.cz. [citado el 6 de junio de 2023]. Disponible en: https://www.prolekare.cz/en/journals/czech-and-slovak-pharmacy/2020-2-13/evaluation-of-adherence-to-treatment-in-patients-suffering-from-diabetes-mellitus-122653
Parra DI, Guevara SLR, Rojas LZ. “Teaching: individual” to improve adherence in hypertension and type 2 diabetes. Br J Community Nurs. 2021; 26(2):84-91. DOI: 10.12968/bjcn.2021.26.2.84
Iqbal MZ, Alqahtani SS, Mubarak N, Shahid S, Mohammed R, Mustafa A, Khan AH, Iqbal MS. The influence of pharmacist-led collaborative care on clinical outcomes in type 2 diabetes mellitus: a multicenter randomized control trial. Front Public Health. 2024; 12:1323102. DOI: 10.3389/fpubh.2024.1323102
Hofer R, Choi H, Mase R, Fagerlin A, Spencer M, Heisler M. Mediators and moderators of improvements in medication adherence: Secondary analysis of a community health worker-led diabetes medication self-management support program. Health Educ Behav. 2017; 44(2):285-96. DOI: 10.1177/1090198116656331
Lindenmeyer A, Hearnshaw H, Vermeire E, Van Royen P, Wens J, Biot Y. Interventions to improve adherence to medication in people with type 2 diabetes mellitus: a review of the literature on the role of pharmacists. J Clin Pharm Ther. 2006; 31(5):409-19. DOI: 10.1111/j.1365-2710.2006.00759.x
Gómez-Huelgas R, Martínez-Castelao A, Artola S, Górriz JL, Menéndez E, en nombre del Grupo de Trabajo para el Documento de Consenso sobre el tratamiento de la diabetes tipo 2 en el paciente con enfermedad renal crónica. Tratamiento de la diabetes tipo 2 en el paciente con enfermedad renal crónica. Med Clin (Barc) . 2014; 142(2):85.e1-10. DOI: 10.1016/j.medcli.2013.10.011
Carro GV, Saurral R, Witman EL, Braver JD, David R, Alterini PA, et al. Diabetic foot attack. Pathophysiological description, clinical presentation, treatment and outcomes. Medicina (B Aires). 2020; 80(5):523-30.
Reyes-García R, Moreno-Pérez Ó, Tejera-Pérez C, Fernández-García D, Bellido-Castañeda V, de la Torre Casares ML, et al. Document on a comprehensive approach to type 2 diabetes mellitus. Endocrinol Diabetes Nutr (Engl ) . 2019; 66(7):443-58. DOI: 0.1016/j.endinu.2018.10.010
Salvador J, Gaztambide S. In process citation. Med Clin (Barc) [Internet]. 2014; 143 Suppl 2:1. DOI: 10.1016/S0025-7753(14)70100-9
Wanner C, Inzucchi SE, Lachin JM, Fitchett D, von Eynatten M, Mattheus M, et al. Empagliflozin and progression of kidney disease in type 2 diabetes. N Engl J Med. 2016; 375(4):323-34. DOI: 10.1056/NEJMoa1515920
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Johan Sebastian Rosero-Gonzalez, Julian Andres Medina-Restrepo, Vicente Benavides-Cordoba
This work is licensed under a Creative Commons Attribution 4.0 International License.
La Revista Salutem Scientia Spiritus usa la licencia Creative Commons de Atribución – No comercial – Sin derivar: Los textos de la revista son posibles de ser descargados en versión PDF siempre que sea reconocida la autoría y el texto no tenga modificaciones de ningún tipo.
