Biomarcadores de la leucemia linfoblástica aguda con compromiso del sistema nervioso central en la infancia.
Resumen
La leucemia linfoblástica aguda infantil es una enfermedad de gran importancia, en la que se da una producción excesiva de linfocitos inmaduros. A su vez, se ha visto que es la forma de cáncer más común en niños, y se ha encontrado en menor medida que es consistente con alteraciones del sistema nervioso central. La leucemia linfoblástica aguda es un tipo de cáncer, el cual se ha visto que es curable en un 80-90% de las veces, además, en niños la supervivencia a largo plazo representa más del 90%. Los biomarcadores en la actualidad se han vuelto piezas clave en la práctica médica, ya que mejoran y especifican la eficacia con la que se puede iniciar el diagnóstico y tratamiento de un paciente, y evidentemente esto aplica para la leucemia linfoblástica aguda. Se mostraron 4 biomarcadores que fueron el BCL11B, el NOTCH1, el SPP1 Y el SCD, y figuran como opciones muy interesantes y que con el uso adecuado pueden volverse fuertes pilares para detectar la leucemia linfoblástica aguda con sus implicaciones del sistema nervioso central en la infancia.
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Derechos de autor 2024 Santiago Alvarez-Rivera
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