Enfermedad por priones: Revisión de la literatura.
Palabras clave:
Deterioro neurológico, Priones, Manifestaciones clínicas, EncefalitisResumen
La enfermedad por priones, son entidades de origen genético desconocido que ocasiona en los seres humano un sin número de manifestaciones neurológicas que llevan a los pacientes a estados de inmovilidad y deterioro severo, con muy mal pronóstico y con tasas curativas inciertas. Es difícil encontrar en la literatura hallazgos importantes para determinar el diagnóstico clínico y metodología farmacológica para contrarrestar el deterioro de los pacientes que sufren dicha afección. Por lo anterior Se realizó una búsqueda sistemática en la base de datos PubMed. Se incluyeron investigaciones desde 1990 hasta 2020 que abordaran los criterios diagnósticos de la enfermedad por Creutzfeldt-Jackobs en adultos, sus manifestaciones clínicas, diagnóstico y manejo, recomendaciones y guías de manejo para evidenciar la situación de los pacientes quienes presentan este tipo de alteraciones y deterioro neurológico de difícil diagnóstico, para determinar criterios clínicos que puedan dar una orientación clínica para el diagnóstico de estas entidades.
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