Esferocitosis hereditaria en neonatos y su fisiopatología: un enfoque molecular.
Resumen
La esferocitosis hereditaria es una causa de anemia hemolítica que afecta comúnmente a neonatos e infantes; en donde por la forma esferoidal, rigidez y fragilidad de los eritrocitos en sangre periférica se produce la hemólisis. Estos cambios morfológicos son generados por alteraciones genéticas, proteicas y de factores externos a la membrana eritrocitaria, lo cual se traduce en la presencia de las manifestaciones clínicas de la enfermedad, la cual si no recibe un diagnóstico oportuno y tratamiento precoz puede ser responsable de complicaciones leves a severas e incluso la muerte.
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Derechos de autor 2024 Maria Clara Vargas-Zuluaga
Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.
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