Eventos trombóticos en pacientes con síndrome antifosfolípido y su manejo profiláctico.

Autores/as

Palabras clave:

Síndrome antifosfolípido, Trombosis, Anticoagulantes orales directos, Warfarina, Hidroxicloroquina, Omega 3, Antiagregantes plaquetarios

Resumen

El síndrome antifosfolípido (SAF) es una condición clínica cuya principal forma de presentación es la trombosis de diversos lechos vasculares, llevando a múltiples complicaciones que representan una amenaza a la vida de los pacientes. Por lo anterior se tiene como objetivo de esta revisión dar a conocer las recomendaciones más actuales sobre el manejo del síndrome, además de recalcar la existencia de alternativas terapéuticas distintas a los inhibidores de la vitamina K. La exploración de múltiples guías internacionales en cuanto al manejo del SAF permitió establecer que la Warfarina sigue siendo el pilar de manejo para las manifestaciones trombóticas de la enfermedad y que el uso de DOACs no se recomienda para el manejo debido al riesgo de trombosis recurrente asociada a su uso en pacientes con SAF. Se requiere de más ensayos clínicos e investigación para recomendar de forma segura el uso de terapias distintas a Warfarina en pacientes con SAF.

Biografía del autor/a

Manuela Avendaño-Restrepo, Universidad Pontificia Bolivariana Medellín (Colombia)

Estudiante de Medicina.

Citas

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Publicado

2022-06-30

Cómo citar

Moreno-Gomez , F., & Avendaño-Restrepo, M. (2022). Eventos trombóticos en pacientes con síndrome antifosfolípido y su manejo profiláctico. Salutem Scientia Spiritus, 8(2), 50–57. Recuperado a partir de https://revistas.javerianacali.edu.co/index.php/salutemscientiaspiritus/article/view/680

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